Table 3.
Hepatic Triglyceride Content, Adipose Tissue, Body Composition, and Metabolic Control
| Control (n = 12) |
Exercise (n = 12) |
Time × treatment interaction |
|||||
|---|---|---|---|---|---|---|---|
| Baseline | Post-treatment | P value | Baseline | Post-treatment | P value | P value | |
| Hepatic triglyceride content, % | 10 (5) | 11 (5) | .08 | 12 (9) | 10 (6) | .04a | .02b |
| Visceral adipose tissue, cm2 | 173 (75) | 187 (53) | .02a | 191 (86) | 169 (50) | .04a | .01c |
| Subcutaneous adipose tissue, cm2 | 396 (124) | 337 (181) | .24 | 409 (113) | 318 (158) | .08 | .07 |
| Fat mass, kg | 38 (9) | 38 (8) | .37 | 35 (15) | 33 (15) | .07 | .24 |
| Lean body mass, kg | 57 (7) | 57 (7) | .10 | 56 (10) | 58 (10) | .01d | .51 |
| Fasting glucose, mmol/L | 5.8 (1.5) | 5.8 (1.8) | .41 | 6.7 (1.7) | 6.6 (1.6) | .38 | .80 |
| Fasting insulin, pmol/L | 98 (58) | 91 (52) | .18 | 118 (75) | 99 (44) | .23 | .96 |
| HOMA-IR | 1.6 (1.1) | 1.7 (1.0) | .18 | 2.3 (1.4) | 1.9 (0.8) | .26 | .53 |
| HbA1c, mmol/mol | 47 (11) | 49 (15) | .16 | 52 (14) | 50 (13) | .14 | .13 |
| fsOGTT, AUC | 838 (191) | 879 (270) | .23 | 1016 (279) | 980 (329) | .20 | .91 |
NOTE. Values are means (± SD).
AUC, area under the curve; fsOGTT, frequently sampled oral glucose tolerance test; HbA1c, glycated hemoglobin; HOMA-IR, homeostasis model of insulin resistance.
a
Significant difference in baseline vs postintervention (P < .05).
b
Significant difference in time × treatment interaction (P < .05).
c
Significant difference in time × treatment interaction (P < .01).
d
Significant difference in baseline vs postintervention (P < .01).