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TEM images of RNAi-AuNP nanoconstructs with various geometries assembled by a-RNA-n-AuNP and s-RNA-n-AuNP building blocks. Depending on the numbers of RNA ligands on AuNP, (a) Bare-AuNP, (b, c) Dumbbell-like nanoconstructs with a single RNA ligand on AuNP, (d, e, f, i, j, k and l) ring and spherical AuNP nanoconstructs with double and triple strands of RNA on AuNP and (g, h) long and stretched poly(RNA-AuNP) nanoconstructs were observed.
