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. 2017 Jan 1;7(1):9–22. doi: 10.7150/thno.16042

Figure 4.

Figure 4

Physicochemical properties of PEI/RNAi-AuNP nanoformulations in terms of (a) hydrodynamic size changes and (b) UV-VIS spectrum changes before and after forming complexes with PEI polymer. (c) TEM images of PEI/RNAi-AuNP in the presence of appropriate amount of PEI (N/P=30 in PBS) forming a compact and condensed nanoparticle structure and (d) with low concentration of PEI (N/P=1 in PBS). (e) The heat generation efficacy of PEI/RNAi-AuNP was monitored by measuring the temperature change of water as CW laser at 655 nm is being irradiated during 7 min. *** P<0.001 (n = 3).