Table 4.
Atopic disorders and the odds of hypomania aged 22 years
| Hypomania symptoms, OR (95% CI) [p] | ||||||
|---|---|---|---|---|---|---|
| n | Hypomania, no. (%) | Unadjusted | Model 1a | Model 2b | Model 3c | |
| nd | 2880 | 2857 | 1872 | 7809 | ||
| None | 1929 | 134 (6.95) | 1 | 1 | 1 | 1 |
| Asthma | 348 | 27 (7.76) | 1.13 (0.73–1.73) [0.591] | 1.07 (0.69–1.66) [0.775] | 1.27 (0.77–2.11) [0.359] | 1.03 (0.66–1.60) [0.903] |
| Eczema | 385 | 28 (7.27) | 1.05 (0.69–1.60) [0.831] | 1.07 (0.71–1.65) [0.766] | 1.22 (0.74–2.01) [0.444] | 1.06 (0.69–1.62) [0.801] |
| Both | 218 | 18 (8.26) | 1.21 (0.72–2.01) [0.476] | 1.17 (0.70–1.96) [0.561] | 1.00 (0.52–1.93) [0.999] | 1.09 (0.65–1.83) [0.757] |
OR, Odds ratio; CI, confidence interval; HCL-32, Hypomania Checklist; BMI, body mass index.
a
Complete case analysis adjusted for age at time of HCL-32 completion, sex and ethnicity.
b
Complete case analysis adjusted for age at time of HCL-32 completion, sex, ethnicity, socio-economic status, psychological and behavioural problems, BMI and maternal postnatal depression.
c
Values imputed for all participants who answered the question about atopy aged 10 years (n = 7809) and adjusted for age at time of HCL-32 completion, sex, ethnicity, socio-economic status, psychological and behavioural problems, BMI and maternal postnatal depression.
d
Number of participants in each model.