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. 2017 Jan 1;34(1):192–203. doi: 10.1089/neu.2015.4340

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Copyright 2016, Mary Ann Liebert, Inc.

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FIG. 4. — Vascular smooth muscle sensitivity to nitric oxide (NO) and contractility are not altered after traumatic brain injury (TBI). (A) Sensitivity to NO was determined using the NO donor spermine NONOate (0.001–1 μM) in the presence of Nω-nitro-l-arginine (l-NNA) (100 μM) in pressurized (80 mm Hg) mesenteric arteries from control (n = 5) and TBI (n = 5) rats. (B) Smooth muscle contractility was determined by establishing U46619 concentration-response relationships in pressurized (40 mm Hg) mesenteric arteries from control (n = 4) and TBI (n = 3) rats.