Figure 2.

The simulation algorithm. The females in the population on day d are described by the variables $({A_W}_{i,d},{A_T}_{i,d})$ (adults, i denotes age) and $({E_W}_d,{E_T}_d)$ (juveniles), where the subscript W or T denotes wildtype or transgenic. The parameter ${\mu }_i$ is the probability an adult female dies at age i (derived from the survivorship function shown in Figure 1A), and ${\mathsf{\Phi }}_W$ and ${\mathsf{\Phi }}_T$ are the probability vectors of pupation after one, two, or three days (Figure 1B). The probability that a given egg is transgenic is half the fraction of transgenic individuals in the adult female population because all transgenic females are hemizygous (their fathers are non-transgenic), and Mendelian inheritance of the transgene has been confirmed experimentally [13,22].