Table 1.

Mutations in the sodium channel proteins that are associated with pyrethroid resistance in Aedes aegypti.

Mutation 1	Original Numbering 2	Year 3	Country	Reference
L982W	L75W	2003	Vietnam	[31]
I1011M + G923V	I104M + G16V	2003	Brazil, Guyana, and Martinique	[31]
I1011V		2007	Multiple Latin American Thailand	[32] [47]
V1016G	V109G	2003	Indonesia	[31]
			Thailand	[31,46,47]
V1016G + S989P		2010	Thailand	[37,38,39]
			Malaysia	[41]
V1016G + F1534C		2015	Singapore	[42]
V1016G + F1534C + S989P		2011	Thailand	[34]
			Myanmar	[44]
			Indonesia	[45]
			China	[43]
V1016G + D1763Y	D1794Y	2009	Taiwan	[40]
V1016I			Multiple Latin American	[32]
F1534C	F1269C	2008	Vietnam	[33]
	F1552C		Thailand	[34,35,36]
F1534C + V1016I		2013	Venezuela	[48]
			French overseas territories	[49]
			Brazil	[50,51,52]
			Mexico	[53]
			United States	[54]
			Ghana	[55]
F1534C + T1520I		2015	India	[56]

¹ Mutations are numbered according to the amino acid sequence of Vssc1 deposited in GenBank (Accession no: AAB47604); ² Refers to the numbering of mutations in the original paper; ³ Refers to the year that the mutation was first reported.