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. 2016 Jun 13;28(1):185–196. doi: 10.1681/ASN.2015070820

Figure 1.

Figure 1.

T-bet+ Treg cells expand during cGN. (A) Representative FACS plots showing renal T-bet+Foxp3+ Treg1 cells at the indicated time points after induction of NTN. (B and C) Quantification of (B) renal and (C) splenic T-bet+Foxp3+ Treg1 and T-bet+Foxp3− Th1 cells as percentages of CD4+ or Foxp3+ cells at the indicated time points after induction of NTN; n≥5 C57BL/6 mice were analyzed at each time point. (D) FACS analysis of surface molecule expression on the indicated splenic Treg cell populations at day 8 after induction of NTN; n=8 C57BL/6 mice were analyzed. Circles in D represent individual animals, and horizontal lines represent mean values. Error bars represent SEM. *P<0.05; **P<0.01; ***P<0.001.