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. 2016 Jun 27;28(1):218–229. doi: 10.1681/ASN.2015121376

Figure 4.

Figure 4.

Necroptosis regulatory proteins are upregulated in FA-induced AKI. Kidney RIPK3 and MLKL levels were assessed in mice with AKI over time. (A) RIPK3 and MLKL mRNA expression is increased in a time-dependent fashion during AKI. Mean±SEM of five animals per group. **P<0.001 versus control. (B) Time course of MLKL protein expression in AKI assessed by Western blot. Quantification and representative Western blot. Mean±SEM of five animals per group. **P<0.004 versus control.