Table 1.
Distribution of 10-pS Cl- channels in the DCT and TAL of Clcnk2+/+ and Clcnk2−/− mice
| Part of the Renal Tubule | Status | F | G, pS | NPo |
|---|---|---|---|---|
| DCT [2] | WT (9) | 1 | 9.3±0.5 (9) | 12.0±4.2 (9) |
| DCT [3] | KO (13) | 0 | NA | NA |
| CNT/CCD [4] | WT (24) | 0.70 | 10.9±0.6 (17) | 34.5±9.6 (14) |
| CNT/CCD [3] | KO (10) | 0 | NA | NA |
| TAL [3] | WT (14) | 0.85 | 7.7±0.6 (12) | 13.9±5.5 (10) |
| TAL [2] | KO (13) | 0 | NA | NA |
[n], number of mice used in the experiments; (n), number of measurements. F, frequency for detecting channel activity; G, pS, unit conductance in picosiemens; NPo, channel activity or normalized current due to 10-pS Cl− channels; NA, not available.