Table 2.

AKI definition and staging according to KDIGO criteria - modified from reference (8)

AKI is defined as any of the following:
1	Increase in sCr ≥0.3 mg/dL (≥26.5 μmol/L) within 48 hours; or
2	Increase in sCr ≥1.5 times baseline, which is known or presumed to have occurred within the prior 7 days; or
3	Urine volume <0.5 mL/kg/h for 6 hours.
AKI is staged for severity according to the following criteria
Stage 1	1.5–1.9 times baseline OR ≥0.3 mg/dL (≥26.5 μmol/L) absolute increase in sCr	Urine volume <0.5 mL/kg/h for 6–12 hours
Stage 2	sCr ≥2.0–2.9 times baseline sCr ≥3.0 times from baseline OR	Urine volume <0.5 mL/kg/h for ≥12 hours
Stage 3	Increase in sCr to ≥4.0 mg/dL(≥353.6 μmol/L) OR Initiation of renal replacement therapy OR, In patients <18 years, decrease in eGFR to <35 mL/min per 1.73 m2	Urine volume <0.3 mL/kg/h for ≥24 hours OR Anuria for ≥12 hours

sCr=serum creatinine, eGFR= estimated glomerular filtration rate