Table 1.
Clinical Characteristics of the Cohorts
| GAMES-Pilot | Neuroimaging controls | Two-sided p value† | Biomarker controls | Two-sided p value‡ | |
|---|---|---|---|---|---|
| (N=10) | (N=8) | (N=15) | |||
| Age, mean ± SD | 51±15 | 63±12 | 0.07 | 74±14 | <0.01 |
| Male % (n) | 30% (3) | 88% (7) | 0.02 | 60% (9) | 0.23 |
| Baseline NIHSS, median [IQR] | 19 [15, 23] | 19 [16, 21] | 0.72 | 17 [15, 23] | 0.68 |
| Baseline DWI volume (cm3), mean ± SD | 102 ± 23 | 117 ± 68 | 0.55 | 117 ± 38 | 0.22 |
| Admission glucose (mg/dL), mean ± SD | 123 ± 16 | 138 ± 28 | 0.33 | 129 ± 21 | 0.43 |
| Medical History % (n) | |||||
| Hypertension | 50% (5) | 63% (5) | 0.66 | 67% (10) | 0.44 |
| Diabetes | 20% (2) | 13% (1) | 1.00 | 0% (0) | 0.15 |
| Hyperlipidemia | 30% (3) | 63% (5) | 0.34 | 40% (6) | 0.69 |
| Prior ischemic stroke | 40% (4) | 0% (0) | 0.09 | 27% (4) | 0.67 |
| Atrial fibrillation | 10% (1) | 25% (2) | 0.56 | 60% (9) | 0.02 |
| Coronary artery disease | 10% (1) | 25% (2) | 0.56 | 13% (2) | 1.00 |
| Intravenous Thrombolysis % (n) | 90% (9) | 0% (0) | <0.01 | 80% (12) | 1.00 |
†
Comparison between GAMES-Pilot and Neuroimaging cohort.
‡
Comparison between GAMES-Pilot and Biomarker cohort.