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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: ACS Chem Biol. 2016 Feb 10;11(4):1128–1136. doi: 10.1021/acschembio.5b00993

Figure 2.

Figure 2

MIN6 cell phospho-ERK1/2 response to glucose in the presence of palmitate preserved by ISX. (A) Gene set enrichment analysis indicating a significant normalized enrichment score (NES) for ISX-induced genes in the fatty acyl-CoA biosynthesis pathway. (B) Representative immunoblots for phospho- and total ERK1/2. Below shows a bar graph of the average and SE of three independent experiments. Phospho/total-ERK1/2 ratio was normalized to basal BSA DMSO control.