Table 1.
Study | Sample size | Dropouts | Intervention design | Primary outcome measure | Secondary outcome measure(s) | Follow-up duration | Control | Risk of bias | PEDro score |
---|---|---|---|---|---|---|---|---|---|
Allen et al 27 | Intervention (I) 190; Control (C) 190 |
I: 25 C: 36 |
Comprehensive post-discharge care management intervention; assessment by nurse in participant’s home; reviewed by the treating medical team. Patient care plans developed. Periodic telephone calls to assess change | None stated | Neuromotor function (measured using NIHSS, Timed Up and Go test, and physical performance test); institution time (days spent hospitalised or in a nursing home during 6-month follow-up); death; quality of life (stroke-specific QOL scale); systolic and diastolic blood pressure (mmHg), depression (CES-D scale), medication appropriateness (an investigator generated tool), haemoglobin A1c (%), total cholesterol (mg/dL), self-reported falls and incontinence; stroke knowledge and lifestyle modification (an investigator-generated questionnaire that assesses knowledge of stroke risk factors and health behaviours) | 6 months | Usual post-discharge care planning | Low | 9 |
Tanne et al 30 | I: 43 C: 9 |
I: 2 C: 2 |
Education on vascular risk, physical exercise and healthy lifestyle; supervised exercise programme, twice/week for 3 months (15 minutes warm-up, 45 minutes on treadmill, stair machine and bicycle at 60–70% of maximal heart rate); prescribed by physiologist; supervised by physical therapy and cardiac rehabilitation staff. Exercise prescription adjusted if capacity improved | Physical fitness — maximal exercise test, 6-minute walk test (metres walked) | Resting heart rate (BPM) and resting systolic blood pressure (mmHg) | 3 months | Usual post-TIA/stroke care | High. Pilot non-random trial | 6 |
Toledano-Zarhi et al 28 | I:14 C: 14 |
I: 1 C: 0 |
Exercise group enrolled in 6-week supervised exercise programme (3 hours weekly: 2 sessions of 35–55 minutes on treadmill, hand-bike, and bicycle, supervised by physical therapy and cardiac rehabilitation staff: 8 progressive stages; also, 45–55 minutes group practice for strength, flexibility, and coordination Exercise prescription adjusted if capacity improved | Exercise capacity — maximal exercise test, 6-minute walk test (metres walked) | Adverse events (for example strokes or falls) | 6 weeks | Home-exercise booklet, advising strength and flexibility exercises, plus normal routine | Uncertain | 7 |
Boysen et al 29 | I: 157 C: 157 |
I: 24 C: 14 |
Repeated encouragement and verbal instruction on being physically active given by a physiotherapist or neurologist | Physical activity assessed with the Physical Activity Scale for the Elderly | Clinical events, for example number of strokes, or hospitalisations | 2 years | Verbal information on benefits of physical activity | Low risk | 9 |
BPM = beats per minute. CES-D = Center for Epidemiologic Studies - Depression. NIHSS = National Institutes of Health Stroke Scale. PEDro = Physiotherapy Evidence Database. QOL = quality of life. TIA = transient ischaemic attack.