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. 2016 Dec 6;67(654):e57–e66. doi: 10.3399/bjgp16X688369

Table 1.

Information on included studies, risk of bias and PEDro Score

Study Sample size Dropouts Intervention design Primary outcome measure Secondary outcome measure(s) Follow-up duration Control Risk of bias PEDro score
Allen et al 27 Intervention (I) 190;
Control (C) 190
I: 25
C: 36
Comprehensive post-discharge care management intervention; assessment by nurse in participant’s home; reviewed by the treating medical team. Patient care plans developed. Periodic telephone calls to assess change None stated Neuromotor function (measured using NIHSS, Timed Up and Go test, and physical performance test); institution time (days spent hospitalised or in a nursing home during 6-month follow-up); death; quality of life (stroke-specific QOL scale); systolic and diastolic blood pressure (mmHg), depression (CES-D scale), medication appropriateness (an investigator generated tool), haemoglobin A1c (%), total cholesterol (mg/dL), self-reported falls and incontinence; stroke knowledge and lifestyle modification (an investigator-generated questionnaire that assesses knowledge of stroke risk factors and health behaviours) 6 months Usual post-discharge care planning Low 9
Tanne et al 30 I: 43
C: 9
I: 2
C: 2
Education on vascular risk, physical exercise and healthy lifestyle; supervised exercise programme, twice/week for 3 months (15 minutes warm-up, 45 minutes on treadmill, stair machine and bicycle at 60–70% of maximal heart rate); prescribed by physiologist; supervised by physical therapy and cardiac rehabilitation staff. Exercise prescription adjusted if capacity improved Physical fitness — maximal exercise test, 6-minute walk test (metres walked) Resting heart rate (BPM) and resting systolic blood pressure (mmHg) 3 months Usual post-TIA/stroke care High. Pilot non-random trial 6
Toledano-Zarhi et al 28 I:14
C: 14
I: 1
C: 0
Exercise group enrolled in 6-week supervised exercise programme (3 hours weekly: 2 sessions of 35–55 minutes on treadmill, hand-bike, and bicycle, supervised by physical therapy and cardiac rehabilitation staff: 8 progressive stages; also, 45–55 minutes group practice for strength, flexibility, and coordination Exercise prescription adjusted if capacity improved Exercise capacity — maximal exercise test, 6-minute walk test (metres walked) Adverse events (for example strokes or falls) 6 weeks Home-exercise booklet, advising strength and flexibility exercises, plus normal routine Uncertain 7
Boysen et al 29 I: 157
C: 157
I: 24
C: 14
Repeated encouragement and verbal instruction on being physically active given by a physiotherapist or neurologist Physical activity assessed with the Physical Activity Scale for the Elderly Clinical events, for example number of strokes, or hospitalisations 2 years Verbal information on benefits of physical activity Low risk 9

BPM = beats per minute. CES-D = Center for Epidemiologic Studies - Depression. NIHSS = National Institutes of Health Stroke Scale. PEDro = Physiotherapy Evidence Database. QOL = quality of life. TIA = transient ischaemic attack.