Table 2.
Description for demographic and brain biomarkers of interest.
| Variable | Description of data extraction | Coding |
|---|---|---|
| Demographics | ||
| Age | In years at time of stroke | – |
| Days post stroke | Days, converted from months (*30) or years (*12*30) as required | 0–30 days; 31–90 days; 91–180 days, > 180 days |
| Sex | Male, Female | – |
| Brain biomarkers | ||
| Lesion volume | cm3 | – |
| Lesion side | Right, left | – |
| Lesion location | As reported in text; only extracted if reported from CT or MRI at time of study data collection | Cortical, subcortical, mixed (cortical + subcortical), non-specific haemorrhage |
| Motor evoked potential | At rest, and location of electromyographic collection | Motor evoked potential response: present or absent Location: hand, any muscle with an action on the fingers or thumb; forearm, any muscle with an action on the wrist or forearm; or upper arm, any muscle with an action at the elbow or shoulder |
| Corticospinal tract | Fractional anisotropy of segment, whole tract or region for the ipsilesional and contralesional hemisphere | Asymmetry index [contralesional − ipsilesional fractional anisotropy] / [contralesional + ipsilesional fractional anisotropy] |