Table 2.
The GO terms associated with the GEAs in the mPFC.
| Category | Term | FE | P-values |
|---|---|---|---|
| <OVX-induced up-regulation> | |||
| GOTERM_MF_DIRECT | GO:0003735∼structural constituent of ribosome | 2.25 | 2.82E-23 |
| GOTERM_CC_DIRECT | GO:0005840∼ribosome | 2.28 | 7.48E-22 |
| GOTERM_BP_DIRECT | GO:0006412∼translation | 1.92 | 1.31E-19 |
| GOTERM_CC_DIRECT | GO:0022625∼cytosolic large ribosomal subunit | 2.85 | 4.74E-14 |
| GOTERM_CC_DIRECT | GO:0005739∼mitochondrion | 1.29 | 2.18E-11 |
| GOTERM_CC_DIRECT | GO:0030529∼intracellular ribonucleoprotein complex | 1.68 | 2.69E-10 |
| GOTERM_MF_DIRECT | GO:0044822∼poly(A) RNA binding | 1.27 | 2.11E-05 |
| GOTERM_CC_DIRECT | GO:0005743∼mitochondrial inner membrane | 1.45 | 2.12E-04 |
| GOTERM_CC_DIRECT | GO:0015935∼small ribosomal subunit | 2.66 | 1.97E-03 |
| GOTERM_CC_DIRECT | GO:0022627∼cytosolic small ribosomal subunit | 2.22 | 5.33E-03 |
| <OVX-induced down-regulation> | |||
| GOTERM_MF_DIRECT | GO:0004984∼olfactory receptor activity | 7.23 | 3.96E-08 |
| GOTERM_BP_DIRECT | GO:0007608∼sensory perception of smell | 5.13 | 5.55E-07 |
| GOTERM_CC_DIRECT | GO:0045095∼keratin filament | 5.26 | 2.99E-04 |
| <CMS-induced up-regulation> | |||
| GOTERM_CC_DIRECT | GO:0014069∼postsynaptic density | 2.34 | 0.04 |
| <CMS-induced down-regulation> | |||
| None | |||
The GO terms were determined by DAVID (ver. 6.8) analysis. GO terms with a Bonferroni P-value less than 0.05 were considered statistically significant. GO terms shown in boldface indicate the overlap between the two tissues (see Table 3). FE: Fold enrichment.