Fig. 8.

Cytoprotective effect of CGF extract measured as % cell viability by MTT assay. Pre-treatment with CGF extract was performed on alloxan-induced RINm5F cell damage. The IC₅₀ of alloxan (9 mM) was used to induce cell death after pre-treatment with CGF extract. In panel, Control is normal cells whereas Alloxan is cells treated with alloxan alone. In panel CGFs cells were treated with CGF extract at concentrations of 62.5, 125, 250 and 500 μg/mL, respectively for 24 h before exposure of alloxan. Values are expressed as mean ± SD of results obtained from minimum of three independent experiments. *^ap < 0.05 statistically significant difference compared to control. *^b p < 0.05 statistically significant difference compared to alloxan.