Table 2.
Chronic anti-inflammatory activity of BREAF in cotton pellet granuloma test in mice.
| Group | Wet weight (mg) | Dry weight (mg) |
|---|---|---|
| Control | 157.0 ± 10.0 | 74.0 ± 4.6 |
| BREAF (5 mg/kg, p.o.) | 129.0 ± 8.1* (17.8) | 59.0 ± 3.2* (20.2) |
| BREAF (10 mg/kg, p.o.) | 122.0 ± 3.4** (22.2) | 56.0 ± 3.1** (24.3) |
| BREAF (20 mg/kg, p.o.) | 113.0 ± 5.5** (28.0) | 49.0 ± 3.2** (33.7) |
| Dexamethasone (1 mg/kg, p.o.) | 106.0 ± 5.5** (32.4) | 43.0 ± 3.5** (41.8) |
Values in parenthesis indicate % protection in respective groups.
Data represented in mean ± SEM, (n = 6).
*p < 0.05 and **p < 0.01 compared with control group.