Table 1.
Baseline Characteristics and Demographics
| Characteristic | Statistics | Inositol Dose group (mg/kg/day) | a P-value | |||
|---|---|---|---|---|---|---|
| 0 (N=35) | 10 (N=29) | 40 (N=30) | 80 (N=28) | |||
| GA (weeks) | Mean (SD) | 26.5 (0.3) | 26.6(0.3) | 26.7 (0.3) | 26.7 (0.4) | 0.95 |
| Lower GA stratum | 23–26 week n (%) | 19 (54%) | 15 (52%) | 16 (53%) | 14 (50%) | 0.99 |
| Birth weight (grams) | Mean (SD) | 884 (38) | 897 (51) | 939 (45) | 921 (54) | 0.83 |
| Head circumference cm | Mean (SD) | 23.5 (0.4) | 24.1 (0.4) | 25.1 (0.5) | 24.6 (0.4) | 0.10 |
| Gender | Female | 17 (49%) | 15 (52%) | 14 (47%) | 16 (57%) | 0.87 |
| Race | N. American Native | 0 | 3 (10%) | 0 | 0 | 0.12 |
| Asian | 0 | 1 (3%) | 1 (3%) | 0 | ||
| Black | 18 (51%) | 15 (52%) | 12 (40%) | 13 (46%) | ||
| More Than Once Race | 0 | 1 (3%) | 0 | 0 | ||
| White | 17 (49%) | 9 (31%) | 17 (57%) | 15 (54%) | ||
| Ethnicity | Hispanic or Latino | 9 (26%) | 3 (10%) | 7 (23%) | 8 (29%) | 0.35 |
| Antenatal steroids | 32 (91%) | 24 (83%) | 24 (80%) | 26 (93%) | 0.37 | |
| Chorioamnionitis | 5 (14%) | 4 (14%) | 4 (13%) | 3 (11%) | 0.97 | |
| Cesarean Delivery | 21 (60%) | 16 (55%) | 19 (63%) | 14 (50%) | 0.75 | |
| Early onset sepsis | 0 | 0 | 1 (3%) | 0 | 0.38 | |
| Apgar-1 minute | Median (range) | 3 (1–9) | 5 (1–8) | 3 (1–8) | 5 (1–8) | 0.97 |
| Apgar-5 minute | Median (range) | 7 (1–9) | 8 (1–9) | 7 (1–8) | 7 (3–9) | 0.97 |
a
P-values calculated by testing the null hypothesis of equality across all 4 treatment groups using ANOVA techniques for continuous measures, Mantel-Haenszel mean score tests using modified ridit scores for ordinal measures, and chi-square or Fisher’s exact test for nominal measures.