Subject area	Biology
More specific subject area	Heart disease, gene knockdown
Type of data	Tables
How data was acquired	Microarray data in cardiomyocytes generated using Affymetrix GeneAtlas 3′-IVT Express Kit
Data format	Analyzed
Experimental factors	Comparison of inflammatory and mitochondrial gene expression profiles of GPER-deficient versus intact cardiomyocytes from male and female mice
Experimental features	RNA isolation, global gene expression analysis, and bioinformatics analyses using Gene Set Enrichment Analysis (GSEA) software
Data source location	Wake Forest School of Medicine, Winston-Salem, NC, USA
Data accessibility	Dataset is within this article and available in the Gene Expression Omnibus with accession number GEO:GSE86843.