Table 2.
Correlations between intra-iFC scores and ADAS Cog (Mod) scores
| Intrinsic brain network | Correlation coefficient (r) (P value) |
Linear regression |
|---|---|---|
| Control subjects: sex, age, GM atrophy | Adjusted R2 (P value) | |
| lAtt | −0.386 (.001)∗ | 0.131 (.001) |
| rAtt | −0.284 (.020)∗ | 0.067 (.018) |
| aDMN | −0.369 (.002)∗ | 0.123 (.002) |
| pvDMN | −0.566 (<.001)∗ | 0.316 (<.001) |
| pdDMN | −0.412 (.001)∗ | 0.171 (<.001) |
| Aud | −0.425 (<.001)∗ | 0.170 (<.001) |
| Vis | −0.381 (.001)∗ | 0.135 (.001) |
| Sens | −0.263 (.032)∗ | 0.057 (.026) |
Abbreviations: ADAS Cog (Mod), modified version of the Alzheimer's Disease Assessment Scale-cognitive subscale; Aud, auditory network; iFC, intrinsic functional connectivity; lAtt, left attention network; pdDMN, posterior-dorsal default mode network; pvDMN, posterior-ventral default mode network; rAtt, right attention network; Sens, sensorimotor network; Vis, visual network.
NOTE. Pearson product-moment correlation coefficients (r), controlled for age, sex, and GM atrophy, which were significant after multiple comparison correction (corrected a ≤ .006) are indicated by bold values. A linear regression was conducted and estimated adjusted R2 values and associated analysis of variance model significance values are shown (see Fig. 2).
Significant correlations at P ≤ .05, before correction for multiple comparisons.