Table 3.
Comparison of memory impairment in patients with epidermal growth factor receptor (EGFR)‐mutated lung adenocarcinoma and brain metastases treated with EGFR–tyrosine kinase inhibitor (TKI) alone or with whole‐brain radiotherapy (WBRT)
| 6 months | 1 year | >2 years | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Recall | Delayed recall | Recognition | Recall | Delayed recall | Recognition | Recall | Delayed recall | Recognition | |
| EGFR‐TKI alone | 4% (3/78) | 5% (4/78) | 1% (1/78) | 1% (1/67) | 4% (3/67) | 1% (1/67) | 0 (0/30) | 3% (1/30) | 0 (0/30) |
| TKI plus WBRT | 12% (6/50) | 18% (9/50) | 8% (4/50) | 9% (4/43) | 14% (6/43) | 7% (3/43) | 4% (1/25) | 8% (2/25) | 4% (1/25) |