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. 2016 Dec 18;107(12):1721–1729. doi: 10.1111/cas.13084

Figure 5.

Figure 5

(a) EG.7 tumor cells were s.c. transplanted in B6 mice (day 0). After it was confirmed that the transplanted EG.7 cells had established a solid tumor mass, the mice were weekly immunized with OVA 257–264 (OVA) with/without imiquimod (IMQ) and glycyrrhizin (GR) (days 7, 14, and 21) (seven mice/group). The tumor growth and median overall survival (MST) of each group of mice are shown. The tumor growths from day 14 to day 26 in the group given OVA plus imiquimod with or without glycyrrhizin are also shown. Statistical significance was analyzed by anova (one‐sided test). (b) EG.7 or parental EL‐4 tumor cells were s.c. transplanted in B6 mice (day 0) and the mice were weekly treated with imiquimod and glycyrrhizin with/without OVA 257–264 (days 7, 14, and 21) (seven or eight mice/group). The tumor growth of each group of mice is shown. Data are representative of two experiments. NR, not reached.