Table 4. Odds ratio of rapid progression for a panel of uremic solutes.
| Uremic Solute | Crude | Adjusted | ||||||
|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |||||
| CMPF | 0.78 | 0.48 | - | 1.29 | 0.94 | 0.49 | - | 1.81 |
| Hippuric acid | 1.20 | 0.76 | - | 1.90 | 1.50 | 0.77 | - | 2.93 |
| Indole acetic acid | 1.25 | 0.78 | - | 2.01 | 2.07 | 1.07 | - | 4.02 |
| Indoxyl sulfate | 0.84 | 0.52 | - | 1.33 | 0.96 | 0.54 | - | 1.70 |
| Kynurenic acid | 1.42 | 0.83 | - | 2.42 | 1.39 | 0.66 | - | 2.91 |
| Kynurenine | 1.24 | 0.78 | - | 1.99 | 1.37 | 0.76 | - | 2.48 |
| Quinolinic acid | 1.46 | 0.91 | - | 2.34 | 1.21 | 0.66 | - | 2.19 |
| p-Cresyl glucuronide | 0.90 | 0.57 | - | 1.42 | 0.97 | 0.51 | - | 1.84 |
| p-Cresyl sulfate | 1.14 | 0.72 | - | 1.79 | 1.38 | 0.76 | - | 2.53 |
| Phenyl sulfate | 1.12 | 0.71 | - | 1.78 | 1.29 | 0.72 | - | 2.32 |
| Tryptophan | 0.99 | 0.63 | - | 1.57 | 1.18 | 0.63 | - | 2.21 |
Odds ratios (OR) are presented per incremental SD in uremic solute concentration. The adjusted ORs were obtained from a logistic regression corrected for batch, age, diagnosis (congenital disease present), systolic blood pressure, dietary fiber intake, protein intake, proteinuria and serum albumin concentration at baseline. CMPF: 3-carboy-4-methyl-5-propyl-2-furanpropionate.