Fig 7. Inhibition of the edematogenic activity of B. jararaca venom (BjV) by extracts of K. brasiliensis (Kb) (A) and K. pinnata (Kp) (B) in post-treatment protocol.

BjV was injected i.pl. in the right hind paw of mice 5 min before treatment with extract (500 mg/kg, i.p.). Paw thickness was measured during 120 min after venom injection. Edema was expressed as the increase in paw thickness calculated, by the percentage difference between the paw thickness after (at respective time) and before (basal values) venom injection. The points represent the mean ± SEM (n = 5). *p<0.05 and **p<0.01 compared to the group receiving venom alone along with the i.p. injection of 5% castor oil in PBS (Two-way ANOVA followed by the Bonferroni test).