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. 2016 Oct-Dec;8(4):70–81.

Table 1.

The most commonly used peptides that exhibit antibacterial activity and can penetrate through the cell membrane

PEPTIDE AMINO ACID SEQUENCE SECONDARY
STRUCTURE
REFERENCE
Penetratin RQIKIWFQNRRMKWKK α-helical [90]
Tat GRKKRRQRRRPPQ nonstructural, PPII-helical [91]
Pep-1 KETWWETWWTEWSQPKKKRKV α-helical [92]
S413-PV ALWKTLLKKVLKAPKKKRKV α-helical [93]
Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS α-helical [94]
Buforin II TRSSRAGLQFPVGRVHRLLRK α-helical [95]
Apidaecins RP - - - - - PRPPHPR nonstructural [96]
Transportan (TP10) GWTLNSAGYLLGKINLKALAALAKKIL α-helical [97]
MAP KLALKLALKALKAALKLA α-helical [98]
sC18 GLRKRLRKFRNKIKEK α-helical [99]
LL-37 LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES α-helical [100]
Bac-7 PFPRPGPRPIPRPLPFPRPGPRPIPRP PPII- and α-helical [101]