Table 2.
Cox regression models to examine the prognostic factors for overall survival
| Covariate | Hazard Ratio | P | 95% confidence interval |
|---|---|---|---|
| Stage | |||
| 1 | 1.00 | ||
| 2 | 3.78 | 0.10 | 0.78–18.34 |
| 3 | 2.65 | 0.32 | 0.38–18.32 |
| 4 | 2.05 | 0.47 | 0.29–14.60 |
| Surgery + Radiation | |||
| With Radiation* | 1.00 | ||
| Without Radiation | 0.49 | 0.36 | 0.11–2.26 |
| Surgical margin | |||
| Negative* | 1.00 | ||
| Positive | 7.13 | 0.004 | 1.87–27.10 |
*
Reference category
Cox regression modeling showed that positive surgical margin predicted worse overall survival, (hazard ratio=7.1; P=0.004). Adjuvant radiation was not identified as a significant predictor for overall survival (p=0.36).