Figure 4. EMG amplitude during voluntary runway locomotion was significantly reduced by 5‐HT₇ receptor blockade in TA and Add muscles, which came back to pre‐drug level within 30 min after drug application.

In the case of Sol muscles the decrement induced by SB269970 application was not statistically significant (P > 0.05). Abbreviations: Add, adductor muscle; Sol, soleus muscle; TA, tibialis anterior muscle. The significance of the results was tested using Friedman's non‐parametric test followed by Dunn's multiple comparison (^* P < 0.05, ^** P < 0.01, ^*** P < 0.001). The data are presented as means ± SD.