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. 2016 Dec 1;6(12):2755–2771.

Figure 5.

Figure 5

PIM1 overexpression compromises the anti-tumor effect of miR-370 mimic in ESCC cells. A. PIM1 expression is increased by PIM1 vector. B. Overexpression of PIM1 in cells transfected with miR-370 mimic leads to impaired anti-proliferative effect. C. Overexpression of PIM1 in cells transfected with miR-370 mimic leads to increased cell growth. D. Overexpression of PIM1 in cells transfected with miR-370 mimic leads to apoptosis inhibition. E. Overexpression of PIM1 in cells transfected with miR-370 mimic correlates with decreased caspase-3 activity. **P<0.01.