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A, B. Effects of HDIS and CDDP on cell cycle arrest in A549 cells. Lung cancer cell line was incubated for 48 h with HDIs and CDDP alone or in combination in concentration 1.4 (70% IC50) and 2.4 (120% IC50) respectively. Data was analyzed by flow cytometry and results are expressed as mean ± SD of three separate experiments (n = 6 per concentration, **P<0.01, ***P<0.001 versus the control, one-way ANOVA test).
