Figure 4.

Knockdown of USP11 promotes cell growth, migration, and invasion in a YAP-dependent manner in 786-O cells. A. 786-O cells were transfected with control or indicated siRNAs. After 48 h, the cell growth was measured by CCK-8 assay at indicated days. These results show data from at least three independent experiments. B. 786-O cells were transfected with control or indicate siRNAs. Representative images of cell migration and invasion assays are shown on the upper panel, and the quantitative analysis is shown on the right panel of each figure. The mean values (S.D.) of three independent experiments are shown (*, P < 0.05). Migration and invasion assays were performed using Transwell chambers without or with Matrigel as described under Materials and Methods.