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Physcion exerts anti-tumor effect in vivo. A. Physcion suppresses the tumor growth. B. Physcion induces apoptosis in tumor tissues. C. Physcion increases the level of miR-370 in tumor tissue. D. In vivo results confirms the involvement of AMPK/Sp1/DNMT1 signaling in the anti-tumor effect of physcion in xenograft model. **P<0.01.
