Table 2.

Significant initial activations during anticipation of phobia-specific vs. neutral pictures as revealed by ROI analysis.

Region		Phobics > controls					Controls > phobics
		x	y	z	t-Value	mm3	x	y	z	t-Value	mm3
Amygdala	L	− 30	− 7	− 10	4.68	297
ACC	L/R	− 1	46	7	3.79	351a
Insula	L	− 33	− 7	− 9	4.08	378
	R	31	5	− 7	4.15	324
PFC
dmPFC	L						− 16	− 6	55	3.44	189
	R	9	− 6	72	3.24	270	13	− 4	61	3.29	189
vlPFC	L	− 29	38	14	3.11	189
	R	31	57	19	3.48	594
vmPFC	R	18	38	14	3.41	513
	L/R	− 2	48	8	4.29	1836a
Thalamus	L	− 9	− 13	11	3.29	540
Visual cortex
Fusiform gyrus	L	− 41	− 48	− 17	4.39	1107
	L	− 38	− 69	− 20	4.79	945
	R	26	− 44	− 16	4.54	3510

ACC, anterior cingulate cortex; PFC, prefrontal cortex; dmPFC, dorsomedial prefrontal cortex; vlPFC, ventrolateral prefrontal cortex; vmPFC, ventromedial prefrontal cortex; L, left; R, right; (x,y,z), Talairach coordinates of maximally activated voxel (activation threshold: p < 0.05 corrected)

^aThese activation clusters are interconnected.