Table 1.
Demographics and inflammatory marker profiles.
| Variable | Overall n = 90 |
Control n = 62 |
IBS n = 28 |
IBS-D n = 13 |
IBS-C n = 12 |
p-values* |
|---|---|---|---|---|---|---|
| Gender n (%) | ||||||
| Male | 45 (50%) | 33 (53.2%) | 12 (42.9%) | 5 (38.5%) | 5 (41.7%) | NS |
| Female | 45 (50%) | 29 (46.8%) | 16 (57.1%) | 8 (61.5%) | 7 (58.3%) | NS |
| Race n (%) | ||||||
| White | 45 (50%) | 30 (48.4%) | 15 (53.6%) | 8 (61.5%) | 6 (50%) | NS |
| Black | 26 (28.9%) | 17 (27.4%) | 9 (32.1%) | 2 (15.4%) | 6 (50%) | NS |
| Asian | 13 (14.4%) | 10 (16.1%) | 3 (5.2%) | 2 (15.4%) | 0 | NS |
| Other | 6 (6.7%) | 5 (8.1%) | 1 (3.6%) | 1 (7.7%) | 0 | NS |
| Age (yrs) | 27.82 ± 7.85 | 28.22 ± 8.05 | 26.93 ± 7.45 | 26.62 ± 6.99 | 27.50 ± 8.09 | NS |
| LBP (μg/mL) | 18.69 ± 6.82 | 18.26 ± 6.10 | 19.61 ± 8.19 | 22.78 ± 9.89 | 16.56 ± 5.33 | 0.02 |
| CRP (mg/L) | 2.11 ± 3.12 | 2.08 ± 3.12 | 2.18 ± 3.35 | 2.87 ± 4.47 | 1.88 ± 2.03 | NS |
| ESR (mm/h) | 8.71 ± 7.53 | 8.81 ± 7.86 | 8.50 ± 6.89 | 9.15 ± 7.66 | 9.33 ± 6.39 | NS |
IBS = Irritable Bowel Syndrome, IBS-D = Irritable Bowel Syndrome- Diarrhea, IBS-C = Irritable Bowel Syndrome- Constipation, CRP = C-reactive protein, ESR = Erythrocyte sedimentation rate, LBP = Lipopolysaccharide Binding Protein. IBS-Mixed (n = 3) were excluded from analysis of overall IBS group (n = 28). *P-values for LBP are IBS-D compared to control, other comparisons were not significant (NS).