Table 3.
Top 20 genes ranked by highest significance (p-values) for dysregulation in lysozyme-treated, surviving cells at 8 h post-wounding (+ Lyz), compared to baseline at 0 h.*
| Log2 fold change | Lower confidence limit | Upper confidence limit | P-value | FDR | |
|---|---|---|---|---|---|
| COL3A1 | 0.619 | 0.476 | 0.761 | 1.37E-05 | 0.0219 |
| VEGFC | 0.479 | 0.344 | 0.615 | 6.70E-05 | 0.0532 |
| CD9 | 0.515 | 0.351 | 0.679 | 0.000169 | 0.0745 |
| PDGFC | 0.482 | 0.326 | 0.638 | 0.000188 | 0.0745 |
| MAPK8 | 0.664 | 0.442 | 0.886 | 0.000243 | 0.0773 |
| ITGA2 | 0.616 | 0.395 | 0.837 | 0.000394 | 0.104 |
| *ITGB3 | 0.397 | 0.234 | 0.561 | 0.00102 | 0.218 |
| TICAM2 | 0.359 | 0.21 | 0.508 | 0.0011 | 0.218 |
| PIK3CD | 0.731 | 0.416 | 1.05 | 0.00138 | 0.233 |
| IRAK1 | 0.28 | 0.158 | 0.402 | 0.0015 | 0.233 |
| MFGE8 | 0.221 | 0.123 | 0.318 | 0.00161 | 0.233 |
| *PSMB8 | -0.201 | -0.291 | -0.111 | 0.00181 | 0.24 |
| MME | 0.647 | 0.351 | 0.943 | 0.00203 | 0.248 |
| *CSF2RB | 0.734 | 0.379 | 1.09 | 0.00287 | 0.288 |
| *TNFRSF11B | 0.667 | 0.344 | 0.991 | 0.0029 | 0.288 |
| APP | 0.231 | 0.118 | 0.344 | 0.0031 | 0.288 |
| *ILF3 | 0.331 | 0.168 | 0.494 | 0.00322 | 0.288 |
| *IKBKG | -0.411 | -0.614 | -0.208 | 0.00326 | 0.288 |
| CD63 | 0.252 | 0.123 | 0.38 | 0.00405 | 0.338 |
| *CD276 | 0.287 | 0.135 | 0.439 | 0.00497 | 0.395 |
⁎
Marks genes whose mRNA expressions were uniquely altered in the presence of lysozyme.