Table 4.
Top 20 genes ranked by highest significance (p-values) for dysregulation in non-lysozyme-treated, surviving cells at 8 h post-wounding (− Lyz), compared to baseline at 0 h.
| Log2 fold change | Lower confidence limit | Upper confidence limit | P-value | FDR | |
|---|---|---|---|---|---|
| COL3A1 | 0.669 | 0.526 | 0.812 | 7.26E-06 | 0.0115 |
| VEGFC | 0.52 | 0.384 | 0.655 | 3.58E-05 | 0.0285 |
| CD9 | 0.567 | 0.403 | 0.731 | 8.16E-05 | 0.0407 |
| ITGA2 | 0.74 | 0.519 | 0.961 | 0.000102 | 0.0407 |
| PDGFC | 0.488 | 0.332 | 0.644 | 0.000172 | 0.0502 |
| MAPK8 | 0.687 | 0.465 | 0.909 | 0.00019 | 0.0502 |
| NFATC2 | 0.36 | 0.237 | 0.484 | 0.000294 | 0.0658 |
| TICAM2 | 0.425 | 0.276 | 0.574 | 0.000341 | 0.0658 |
| IRAK1 | 0.343 | 0.221 | 0.465 | 0.000373 | 0.0658 |
| HMGB1 | 0.221 | 0.14 | 0.301 | 0.000442 | 0.0702 |
| PIK3CD | 0.827 | 0.512 | 1.14 | 0.000605 | 0.0842 |
| IL6ST | 0.513 | 0.313 | 0.713 | 0.000703 | 0.0842 |
| APP | 0.287 | 0.174 | 0.4 | 0.000754 | 0.0842 |
| PVR | 0.851 | 0.515 | 1.19 | 0.000772 | 0.0842 |
| CD164 | 0.243 | 0.146 | 0.339 | 0.000805 | 0.0842 |
| MAP2K1 | 0.506 | 0.302 | 0.711 | 0.000901 | 0.0842 |
| MFGE8 | 0.241 | 0.144 | 0.338 | 0.000901 | 0.0842 |
| MME | 0.704 | 0.408 | 1 | 0.00118 | 0.101 |
| CD97 | 0.458 | 0.265 | 0.651 | 0.00121 | 0.101 |
| CD63 | 0.301 | 0.172 | 0.43 | 0.00133 | 0.105 |