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. 2016 Dec 1;9(12):1497–1506. doi: 10.1242/dmm.027326

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© 2016. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 5. — MR imaging demonstrates gadolinium enhancement of TB lesions. Representative coronal MR images of 1 mm thick slices of control and M. tuberculosis-infected animals at the site of injection (rows 1 and 2) and posterior to site of injection (rows 3 and 4) at 28 days post-infection. Control animal in first and third row demonstrates normal MRI with T₂-, T₂*-, pre- and post-contrast T₁- weighted images. Row 2 shows hypodense TB lesion in right hemisphere with post-contrast T₁-weighted enhancement of the lesion (yellow arrow) in the M. tuberculosis-infected animal. Row 4 demonstrates enlarged ventricle in the T₂-weighted image with visible post-contrast enhancement in the T₁-weighted image (red arrow) in the M. tuberculosis-infected animal.