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Schematic of experimental timeline. In vivo subarachnoid injection of M. tuberculosis H37Rv at PND 4-8 represents time-point zero. During the experiment, the bacillary burden was quantified and neurobehavioral testing was videotaped and scored. 124I-DPA-713 PET/CT imaging occurred at 21 days post-infection and MR imaging at 28 days post-infection.
