Table 3.

Brain regions with significant between-group differences in nodal efficiency and nodal degree respectively.

Metric	Regions	Category	HC	Non-NPSLE	p value (uncorrected)	T value (p value) of clinical correlations with SLEDAI
Nodal efficiency	IFGoperc.R	Frontal	0.471 ± 0.029 (× e-02)	0.447 ± 0.032(× e-02)	0.0052 ↓	——
	IFGtriang.R	Frontal	0.477 ± 0.031(× e-02)	0.456 ± 0.031(× e-02)	0.0069 ↓	− 0.409 (0.034)
	DCG.L	Paralimbic	0.569 ± 0.045(× e-02)	0.537 ± 0.039(× e-02)	0.0070 ↓	− 0.391 (0.044)
Nodal degree	ORBsup.L	Frontal	0.105 ± 0.011	0.113 ± 0.007	0.0061 ↑	——
	IFGoperc.R	Frontal	0.093 ± 0.009	0.087 ± 0.009	0.0038 ↓	——
	DCG.L	Paralimbic	0.125 ± 0.019	0.111 ± 0.009	0.0026 ↓	− 0.428 (0.026)
	DCG.R	Paralimbic	0.131 ± 0.013	0.123 ± 0.012	0.0041 ↓	——
	IOG.L	Occipital	0.069 ± 0.007	0.075 ± 0.007	0.0072 ↑	− 0.594 (0.001)
	FFG.R	Occipital	0.115 ± 0.016	0.107 ± 0.008	0.0066 ↓	− 0.409 (0.034)
	PCUN.R	Parietal	0.153 ± 0.018	0.143 ± 0.013	0.0055 ↓	——

The values of the nodal efficiency and nodal degree were measured as the AUC values across the sparsity range. The between-group comparisons of the regional properties were performed by using nonparametric permutation test (p < 0.01, uncorrected). The age effect was removed in these comparisons. ——, indicating that the nodal property has no significant correlations with the SLEDAI scores.