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. 2016 Dec 7;5:1822. Originally published 2016 Jul 26. [Version 2] doi: 10.12688/f1000research.9094.2

PMC5200949.1; 2016 Jul 26
PMC5200949.2; 2016 Dec 7

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Copyright: © 2016 Koehn LM et al.

This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Luxol fast blue (LFB) stained transverse cross-sections from the injury site of an uninjured control ( a and b), saline-treated ( c and d) and PcTx1-treated ( e and f) animals. The outlined areas in ( a), ( c) and ( e) are shown at higher magnification in ( b), ( d) and ( f) to illustrate the preservation of myelin in the ventromedial areas of these cords. Note the increased numbers and sizes of myelin-devoid spaces in the saline-treated cord ( d) compared to the PcTx1-treated cord ( f). The saline-treated rat ( c and d) had an initial simplified injury severity score (SIS) of 1.73 and the PcTx1-treated rat ( e and f) had an SIS of 1.9.