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. 2016 Dec 29;14:117. doi: 10.1186/s12915-016-0337-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Reassortment origins and patterns of 4 genomes with segments from different vaccine-associated clades. Schematic figure of segment origins and patterns of intra-subtype reassortment of selected H3N2 reassortant genomes. Approximate segment origins are illustrated on a full genome maximum likelihood phylogenetic tree containing 2091 H3N2 genomes sampled between 2008 and 2014. Single unique reassortants are colored yellow in the tree. Origins and patterns were determined from ML and GiRaF analyses