Table 4.

Regression analysis of mesh properties as predictors of smooth muscle outcomes

	Stiffness		Weight		Pore size
	95% CI	P	95% CI	P	95% CI	P
Grafted
KCl (myofiber function)	26.72 (11.61, 41.83)	<0.001*	0.35 (0.12, 0.59)	0.002*	−0.31 (−0.72, 0.08)	0.125
EFS (nerve function)	6.79 (0.22, 13.35)	0.042*	0.15 (0.04, 0.07)	<0.001*	−0.14 (−0.27, −0.01)	0.033*
Carbachol (receptor function)	−0.52 (−5.47, 4.41)	0.834	0.09 (0.06, 0.12)	<0.001*	−0.08 (−0.14, 0.03)	0.002*
PGP 9.5 (nerve density)	15.62 (3.19, 28.06)	0.013*	0.26 (0.07, 0.46)	0.007*	−0.22 (−0.50, 0.06)	0.122
VAChT (cholinergic)	66.64 (14.43, 118.84)	0.012*	1.11 (0.69, 1.52)	<0.001*	−1.18 (−2.21, −0.14)	0.025*
TH (adrenergic)	28.51 (−2.54, 59.57)	0.072	0.43 (−0.03, 0.91)	0.069	−0.27 (−0.91, 0.37)	0.404
Non-Grafted
KCl (myofiber function)	8.54 (7.86, 9.21)	<0.001*	0.35 (−5.70, 4.13)	0.754	0.01 (−0.10, 0.08)	0.847
EFS (nerve function)	−1.63 (−4.26, 0.98)	0.222	−0.002 (−0.03, 0.03)	0.889	0.03 (−0.01, 0.07)	0.179
Carbachol (receptor)	−0.35 (−4.42, 3.52)	0.856	0.05 (0.01, 0.08)	0.002*	−0.04 (−0.10, 0.01)	0.156
PGP 9.5 (nerve density)	2.22 (0.00, 4.44)	0.049*	0.04 (0.03, 0.05)	<0.001*	−0.06 (−0.07, −0.04)	<0.001*
VAChT (cholinergic)	94.70 (−6.21, 195.61)	0.065	1.47 (−0.28, 3.24)	0.099	−1.18 (−2.21, −0.14)	0.025
TH (adrenergic)	9.83 (−1.86, 21.54)	0.099	0.26 (0.19, 0.33)	<0.001*	−0.33 (−0.43, −0.23)	<0.001*

KCl, potassium chloride; EFS, electrical field stimulation; PGP 9.5, protein gene product 9.5; TH, tyrosine hydroxylase; VAChT, vesicular acetylcholine transporter.

Values above indicate maximum contraction following application of stimulant: estimate (upper confidence interval, lower confidence interval).

^*Significance set at P < 0.05.