Table 1.
Relapse rates among patients with Plasmodium vivax malaria in India
| Site | Year | Treatment | n | Follow-up (months) | % Relapse | Reference |
|---|---|---|---|---|---|---|
| Delhi | 1988 | CQ + PQ (5) | 316 | 60 | 44.3 | 4 |
| 1989 | CQ + PQ (5) | 487 | 48 | 30.2 | ||
| 1990 | CQ + PQ (5) | 497 | 36 | 26.6 | ||
| 1991 | CQ + PQ (5) | 524 | 24 | 28.4 | ||
| 1992 | CQ + PQ (5) | 669 | 12 | 23.3 | ||
| 2001 | CQ + BQ | 219 | 12 | 29.68 | 5 | |
| CQ + PQ (5) | 220 | 12 | 26.82 | |||
| CQ | 224 | 12 | 40.18 | |||
| Mumbai | 1999 | CQ | 6 | 11.7 | 6 | |
| CQ + PQ (5) | 6 | 26.7 | ||||
| CQ + PQ (14) | 6 | 0 | ||||
| Mumbai | 2003 | CQ + PQ (14) | 131 | 21 | 4.60 | 7 |
| CQ | 142 | 21 | 9.20 | |||
| Odisha | 2002 | CQ | 723 | 12 | 8.6 | 8 |
| CQ + PQ (5) | 759 | 12 | 6.5 | |||
| Hardwar | 1989 | CQ + PQ (5) | 725 | 13 | 6.9 | 9 |
| 2001 | CQ + PQ (5) | 5,541 | 12 | 0.1–9.2 | 10 | |
| Mandla | 1990 | CQ + PQ (5) | 995 | 8 | 10.3 | 11 |
| Kheda, Gujarat | 1990 | CQ + PQ (5) | 1,520 | 12 | 2.6 | 12 |
| CQ | 264 | 12 | 18.9 | |||
| 1996 | CQ | 226 | 12 | 28.3 | 13 | |
| CQ + PQ (5) | 173 | 12 | 5.78 | |||
| CQ + PY | 136 | 12 | 27.7 | |||
| Shahjahpur | 1986–1989 | CQ + PQ (5) | 13,720 | 48 | 2.03–23.17 | 14 |
BQ = bulaquine; CQ = chloroquine; PQ = primaquine; PY = pyrimethamine. Numbers in brackets indicate number of days of primaquine therapy.