Table 1.

Risk and odds ratios for relapse with vivax malaria from randomized control trials in Afghanistan and Pakistan (in Afghan refugees) on PQ treatment

Study	Period of observation (months)	Treatment arm*	Relapse risk	Odds ratio (95% confidence interval)†	P value
Leslie and others22	11	Placebo	22/71 (31.0%)	1
	11	14-day PQ	1/55 (1.8%)	0.01 (0.002–0.1)	0.001
	11	8-week PQ	4/75 (5.1%)	0.05 (0.01–0.2)	0.001
Leslie and others21	9	Placebo	86/212 (40.6%)	1
	9	14 day (supervised)	40/211 (19.0%)	0.35 (0.21–0.57)	0.01
	9	14-day (unsupervised)	34/173 (19.7%)	0.37 (0.23–0.59)	0.01
Rowland and others23	12	placebo	49/100 (49%)	1
	12	14-day PQ	32/100 (32%)	0.6 (0.46–0.92)	0.014

PQ = primaquine.

^*All groups received chloroquine.

^†vs. placebo in the same trial.