Fig 6. Parameter estimates using different algorithms.

The data are collected similar to [11] at day 1, 2, 3, 5, 7, 9, five replicates per time point. MH: Metropolis–Hasting estimates are presented as blue histograms of posterior samples; L-BFGS-B: local optimization and confidence intervals estimated with approximate Fisher information are presented with red square points and bars; DE: point estimates of the global optimization algorithm Differential Evolution and weighted bootstrapping samples are presented with black triangles and curves. The vertical red dashed line is the reference value.