TABLE 4.

SIMPER analysis identifying OTUs contributing >0.3% OTU-level dissimilarity between coral health states^a

OTU	Phylum	Class	Order	Family	Genus	Mean abundance (%)		Contribution to dissimilarity (%)
						WS	Healthyb	Individual	Cumulative
4455652	Proteobacteria	Gammaproteobacteria	Enterobacteriales	Enterobacteriaceae		1.61	7.9	4.21	4.2
3991527	Firmicutes	Bacilli	Bacillales	Alicyclobacillaceae	Alicyclobacillus	3.45	3.9	3.38	7.6
NR_42	Proteobacteria	Gammaproteobacteria	Oceanospirillales	Endozoicimonaceae		2.29	2.2	2.18	9.8
NR_46	Proteobacteria	Alphaproteobacteria	Rhizobiales	Hyphomicrobiaceae		3.37	0.0	1.74	11.5
875245	Actinobacteria	Actinobacteria	Actinomycetales	Corynebacteriaceae	Corynebacterium	0.09	3.1	1.58	13.1
NR_23	Proteobacteria	Gammaproteobacteria	Alteromonadales			0	3.0	1.57	14.7
337783	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		2.7	0.0	1.39	16.1
NR_38	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae	Paracoccus	0	2.3	1.2	17.3
221108	Proteobacteria	Gammaproteobacteria	Oceanospirillales	Endozoicimonaceae		1.39	0.7	0.99	18.3
355163	Proteobacteria	Deltaproteobacteria	Spirobacillales			1.79	0.0	0.92	19.2
4441357	Proteobacteria	Gammaproteobacteria	Xanthomonadales	Xanthomonadaceae		0.45	1.4	0.85	20.0
NCR_7	Proteobacteria	Gammaproteobacteria	Oceanospirillales	Endozoicimonaceae		0.67	1.0	0.82	20.8
19540	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		1.49	0.0	0.77	21.6
364960	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		1.33	0.0	0.68	22.3
NCR_1	Proteobacteria	Gammaproteobacteria	Xanthomonadales	Xanthomonadaceae		1.32	0.0	0.68	23.0
219732	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		1.25	0.0	0.64	23.6
4381005	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		1.11	0.1	0.58	24.2
NR_30	Proteobacteria	Gammaproteobacteria	Oceanospirillales	Endozoicimonaceae		0.36	0.9	0.57	24.8
4301240	Proteobacteria	Alphaproteobacteria	Sphingomonadales	Erythrobacteraceae		0.29	0.9	0.57	25.3
1106442	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		0.96	0.0	0.49	25.8
3016239	Proteobacteria	Gammaproteobacteria	Enterobacteriales	Enterobacteriaceae	Serratia	0.32	0.9	0.49	26.3
1000986	Actinobacteria	Actinobacteria	Actinomycetales	Corynebacteriaceae	Corynebacterium	0.03	0.9	0.48	26.8
NR_37	Proteobacteria	Gammaproteobacteria	Oceanospirillales	Endozoicimonaceae		0.46	0.5	0.48	27.3
937813	Firmicutes	Clostridia	Clostridiales	[Tissierellaceae]	Anaerococcus	0.04	0.9	0.47	27.7
904675	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		0.86	0.0	0.44	28.2
327709	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		0.82	0.0	0.42	28.6
NR_96	Proteobacteria	Gammaproteobacteria	Legionellales	Francisellaceae	Francisella	0.82	0.0	0.42	29.0
NCR_12	Firmicutes	Clostridia	Clostridiales	Ruminococcaceae		0	0.8	0.41	29.4
4368477	Cyanobacteria	Synechococcophycideae	Synechococcales	Synechococcaceae	Prochlorococcus	0.11	0.7	0.39	29.8
4421429	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		0.72	0.0	0.38	30.2
4305517	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		0.71	0.0	0.37	30.6
2575651	Firmicutes	Clostridia	Clostridiales	Ruminococcaceae		0	0.7	0.36	30.9
4473129	Proteobacteria	Gammaproteobacteria	Pasteurellales	Pasteurellaceae	Haemophilus	0.17	0.6	0.36	31.3
3244896	Firmicutes	Bacilli	Lactobacillales	Streptococcaceae	Streptococcus	0.51	0.2	0.36	31.6
4402516	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		0.68	0.0	0.35	32.0
NR_57	Cyanobacteria	Synechococcophycideae	Pseudanabaenales	Pseudanabaenaceae		0.68	0.0	0.35	32.3
1046541	Actinobacteria	Actinobacteria	Actinomycetales	Corynebacteriaceae	Corynebacterium	0.01	0.7	0.35	32.7
647864	Proteobacteria	Alphaproteobacteria	Sphingomonadales			0.05	0.6	0.35	33.0
166985	Proteobacteria	Gammaproteobacteria	Oceanospirillales	Endozoicimonaceae		0.5	0.2	0.34	33.4
4352594	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae		0.64	0.0	0.33	33.7
4395697	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae	Paracoccus	0.01	0.6	0.31	34.0
826430	Cyanobacteria	Synechococcophycideae	Synechococcales	Synechococcaceae	Synechococcus	0.24	0.5	0.31	34.3
NR_1	Proteobacteria	Alphaproteobacteria	Rhodospirillales	Rhodospirillaceae	Skermanella	0	0.6	0.31	34.7
1909414	Proteobacteria	Alphaproteobacteria	Rhodobacterales	Rhodobacteraceae	Paracoccus	0.14	0.5	0.31	35.0

^aRhodobacteraceae OTUs are shown in bold. Abbreviations: SIMPER, similarity percentages; WS, disease lesion on diseased colony; NR, New.ReferenceOTU; NCR, New.CleanUp.ReferenceOTU.

^bIncludes both HD (healthy region on diseased colony) and healthy (healthy region on healthy colony) states.