FIG 4.

MK2 signaling does not regulate circulating monocytes during A. actinomycetemcomitans pathogenesis. (A) Representative flow cytometry plots of peripheral blood CD11b⁺ CCR1⁺, CD11b⁺ CCR2⁺, and CD11b⁺ CCR5⁺ cells from Mk2^+/+ and Mk2^−/− mice treated with PBS vehicle or A. actinomycetemcomitans (A.a.) for 3 days. Q1 to Q4, quadrants 1 to 4, respectively. (B) Quantification of percent positive CD11b⁺ CCR1⁺, CD11b⁺ CCR2⁺, and CD11b⁺ CCR5⁺ cells from Mk2^+/+ and Mk2^−/− mice treated with PBS vehicle or A. actinomycetemcomitans for 3 days (n = 4). Data are expressed as means ± SEMs. *, P ≤ 0.05.