Table 1. Presence of B19V genomic sequence in the blood DNA of RA patients and healthy persons.
The values marked by stars are significant according to Fisher’s exact tests: *P<0.05, **P<0.0005. B19V, Parvovirus B19; B19+, parvovirus B19 DNA positive; B19−, parvovirus B19 DNA negative; RA, rheumatoid arthritis; Contr., healthy persons.
| Investigated persons (total) | Age±sd (years) | B19+ samples | B19− samples | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Whole blood | Cell-free blood plasma |
Whole blood and cell-free blood plasma | All positive | N | % Total | |||||||
| N | % Total | N | % Total | N | % Total | N | % Total | |||||
| Females | ||||||||||||
| Contr. | 37 | 50.3±10.4 | 6 | 16.2 | 1 | 2.7 | 0 | 0 | 7 | 18.92 | 30 | 81.08 |
| RA | 99 | 57.3±13.0 | 6 | 6.1 | 12 | 12.1 | 6 | 6.1 | 24 | 24.24 | 75 | 75.76 |
| Males | ||||||||||||
| Contr. | 12 | 49.8±13.8 | 2 | 16.66 | 0 | 0 | 0 | 0 | 2 | 16.66 | 10 | 83.33 |
| RA | 19 | 63.5±12.7 | 0 | 0 | 4 | 21.1 | 2 | 10.5 | 6 | 31.58 | 13 | 68.42 |
| All investigated (males+females) | ||||||||||||
| Contr. | 49 | 50.2±11.3 | 8 | 16.3** | 1 | 2.0* | 0 | 0 | 9 | 18.37 | 40 | 81.63 |
| RA | 118 | 58.3±13.0 | 6 | 5.1** | 16 | 13.6* | 8 | 6.8 | 30 | 25.42 | 88 | 75.58 |