Table 3. Diagnostic Performance of LS, APRI, FIB-4, AST/ALT, and FibroQ for Determination of Fiibrosis Stage in Untreated and Treated Patients, Expressed as Area Under the Curve ± Standard Error (AUC ± SE) in ROC Analysis.

	F1 Versus F2 - 4		F1-2 Versus F3 - F4		F1-3 Versus F4
	Therapy Naive	Treated	Therapy Naive	Treated	Therapy Naive	Treated
LS, kPa	0.809 ± 0.09a	0.813 ± 0.1	0.822 ± 0.08a	0.815 ± 0.1a	0.966 ± 0.034b	0.754 ± 0.15
APRI	0.689 ± 0.1	0.5 ± 0.15	0.556 ± 0.1	0.723 ± 0.12	0.615 ± 0.1	0.815 ± 0.12a
FIB-4	0.77 ± 0.08a	0.344 ± 0.15	0.655 ± 0.09	0.708 ± 0.15	0.782 ± 0.094a	0.831 ± 0.14a
AST/ALT	0.633 ± 0.1	0.375 ± 0.14	0.671 ± 0.1	0.554 ± 0.14	0.908 ± 0.071a	0.615 ± 0.15
FibroQ	0.765 ± 0.09a	0.406 ± 0.12	0.78 ± 0.08a	0.738 ± 0.13	0.977 ± 0.03b	0.846 ± 0.14a

^aP<0.05.

^bP < 0.001.